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Updated December 2025

Best Online GLP-1 Weight Loss Programs 2025

Comprehensive programs combining GLP-1 medications with coaching, support, and lifestyle guidance. Find the complete weight loss program that fits your needs and budget.

10

Top Programs

30K+

Reviews Analyzed

15-20%

Average Weight Loss

$99

Starting Price

What Makes a Complete GLP-1 Weight Loss Program?

A comprehensive GLP-1 weight loss program goes beyond just prescribing medication. The best programs combine prescription GLP-1 medications (semaglutide or tirzepatide) with personalized coaching, nutritional guidance, medical oversight, and ongoing support to help you achieve sustainable weight loss.

While some telehealth providers simply ship medication, complete programs offer structured support systems including behavioral coaching, dietary planning, exercise guidance, and regular check-ins with healthcare providers. This holistic approach leads to better results and helps patients maintain their weight loss long-term.

Key Components of Top Programs

  • Medication: FDA-approved or compounded GLP-1 medications with dosing adjustments
  • Medical Oversight: Regular consultations with licensed physicians or nurse practitioners
  • Health Coaching: Personalized guidance on nutrition, exercise, and lifestyle changes
  • Support System: Access to care teams, messaging with providers, and community resources
  • Tracking & Accountability: Apps, check-ins, and progress monitoring

The programs ranked below offer varying levels of support and coaching. Some focus heavily on behavioral change, while others emphasize medical management. Choose based on your personal needs, budget, and the level of support you want.

BREAKING NEWS - December 22, 2025

FDA Approves First Oral GLP-1 for Weight Loss

Wegovy pill offers patients a new no-injection option with up to 17% weight loss in clinical trials. Available January 2026 starting at $149/month with savings offers.

Quick Program Comparison

Compare top programs at a glance

ProgramPriceRatingCoachingBest Feature
Coreage RX$99/mo
4.4
✓ PersonalizedBest overall value
Remedy Meds$299/mo
4.3
✓ IncludedMoney-back guarantee
Amble Health$225/mo
4.2
✓ Included34 lbs average loss
Calibrate$159/mo
4.3
✓ Weekly sessions1-year metabolic program
Brello Health$133/mo
3.7
✓ Dietitian callsBest value

Scroll down for complete rankings and detailed reviews of all programs

#1

Coreage RX

Best Overall
4.4
(850 reviews)From $99/mo

Best for: Those wanting affordable personalized care with exceptional value

Program Features:

  • Industry-leading low price at just $99/month
  • Top-rated personalized weight loss support
  • HIPAA compliant telehealth platform
  • Licensed healthcare providers in Texas
  • Responsive customer service
  • Transparent pricing with no hidden fees
#2

Remedy Meds

Most Complete
4.3
(8,400 reviews)From $299/mo

Best for: Those wanting a comprehensive program with a results guarantee

Program Features:

  • All-inclusive: medication, coaching, and blood work
  • Money-back guarantee if you don't lose 10% in 4 months
  • Unlimited clinician access via messaging
  • Free overnight shipping on all orders
  • LegitScript Certified for safety
  • Over 40,000 patients served successfully
#3

Amble Health

Best Results
4.2
(2,351 reviews)From $225/mo

Best for: Those prioritizing proven weight loss results with comprehensive support

Program Features:

  • Average member weight loss of 34 lbs (15% body weight)
  • 9 out of 10 members saw waist shrink by at least 1 inch
  • All-inclusive flat-rate pricing
  • Includes consult, medication, and supplies
  • Fast 24-hour customer service
  • Proven clinical outcomes
#4

Calibrate

Best Coaching
4.3
(5,200 reviews)From $159/mo

Best for: Those committed to a structured year-long program with intensive coaching

Program Features:

  • Comprehensive one-year metabolic reset program
  • Weekly video coaching sessions
  • Personalized nutrition and lifestyle plans
  • Focus on long-term metabolic health
  • Strong clinical outcomes data
  • Insurance coverage options available
#5

Brello Health

Best Value
3.7
(2,524 reviews)From $133/mo

Best for: Budget-conscious patients wanting coaching without premium pricing

Program Features:

  • Includes personalized health coaching
  • Dietitian-led Zoom coaching calls
  • B6 (Pyridoxine) included for nausea reduction
  • Affordable 3-month supply ($399 total)
  • Large customer base with transparent reviews
  • Supportive community features
#6

Noom Med

Behavior Focus
4.1
(4,500 reviews)From $149/mo

Best for: Those wanting to address psychological aspects of eating and weight loss

Program Features:

  • Psychology-based behavior change program
  • Combines medication with habit formation
  • Daily lessons and interactive coaching
  • Established brand with large user base
  • App-based tracking and support
  • Insurance may cover costs
#7

Found

Science-First
4.2
(3,800 reviews)From $99/mo

Best for: Those wanting a science-driven program at an affordable price

Program Features:

  • Affordable $99/month membership
  • Personalized based on your biology
  • Board-certified physician oversight
  • Comprehensive health assessments
  • Science-backed treatment approach
  • Focus on sustainable lifestyle changes
#8

Sequence

Insurance Help
4.4
(2,800 reviews)From $99/mo

Best for: Those wanting help navigating insurance for brand-name medications

Program Features:

  • Insurance navigation and coverage support
  • Dedicated care coordinators
  • Low membership fee structure
  • Regular check-ins with providers
  • Comprehensive health platform
  • Focus on sustainable results
#9

Mochi Health

Expert Care
4.5
(1,500 reviews)From $179/mo

Best for: Those wanting specialized obesity medicine expertise

Program Features:

  • Board-certified obesity medicine specialists
  • Comprehensive metabolic health approach
  • Personalized treatment plans
  • Strong clinical outcomes focus
  • Regular provider consultations
  • Growing patient community
#10

Form Health

Medical Team
4.4
(1,200 reviews)From $149/mo

Best for: Those wanting a full medical team approach

Program Features:

  • Team-based medical approach
  • Board-certified obesity physicians
  • Registered dietitians on staff
  • Comprehensive care coordination
  • Insurance accepted for many plans
  • Focus on sustainable results

What to Expect from a GLP-1 Program

Program Benefits

What comprehensive programs offer

  • Structured support system beyond just medication
  • Personalized coaching and accountability
  • Nutrition and lifestyle guidance
  • Better long-term weight maintenance
  • Access to healthcare team when needed

Typical Program Structure

How most programs work

  • Initial medical consultation and assessment
  • Personalized treatment plan creation
  • Weekly or bi-weekly coaching sessions
  • Regular progress check-ins and adjustments
  • Ongoing medical oversight and dose titration

Program vs. Medication-Only: What's the Difference?

Medication-Only Services:

  • • Simple prescription and delivery
  • • Minimal medical oversight
  • • No coaching or lifestyle support
  • • Lower monthly cost ($83-$150)
  • • Good for self-motivated individuals

Complete Programs:

  • • Medication + comprehensive support
  • • Regular medical check-ins
  • • Coaching and accountability
  • • Higher cost ($149-$299)
  • • Better for those wanting guidance

Expert Insights on Program Success

Keys to maximizing your results

Engage Fully with Your Program

Patients who actively participate in coaching sessions, complete check-ins, and engage with their care team see significantly better results. Don't just take the medication - use all the resources your program provides. Attend virtual sessions, respond to messages, and track your progress consistently.

Tip: Schedule coaching sessions at consistent times to build a routine. Treat them as non-negotiable appointments.

Build Sustainable Habits, Not Quick Fixes

The best programs focus on habit formation rather than restrictive diets. Work with your coach to develop sustainable eating patterns, regular movement you enjoy, and stress management techniques. The goal is lifestyle change that lasts beyond medication.

Focus on:

Adding healthy foods, not just restricting. Build positive habits first.

Track progress:

Beyond weight - energy, mood, sleep, fitness improvements matter too.

Communicate Openly with Your Care Team

Don't hide struggles or side effects from your providers. The best outcomes happen when patients are honest about challenges, barriers, and setbacks. Your care team can adjust your plan, modify dosing, or provide additional support - but only if they know what's happening.

  • Report side effects immediately for dosing adjustments
  • Share emotional or behavioral challenges affecting progress
  • Ask questions about anything you don't understand
  • Discuss long-term maintenance plans early

Commit to the Full Duration

Most structured programs run 6-12 months for a reason. Sustainable weight loss and habit change take time. Patients who complete full programs and transition to maintenance plans have much better long-term success than those who stop after a few months.

Remember: Weight loss typically plateaus around 12-18 months. Programs help you navigate this plateau and transition to maintenance, which is where many people struggle without support.

How to Choose the Right Program

Key factors to consider when selecting your program

1. Assess Your Support Needs

How much help do you want?

  • • Are you self-motivated or do you need accountability?
  • • Do you want regular coaching or occasional check-ins?
  • • Do you need help with nutrition and meal planning?
  • • Would behavioral psychology support help you?
  • • Do you prefer group support or 1-on-1 coaching?

2. Compare Value vs. Cost

What's included in the price?

  • • Medication included or priced separately?
  • • How many coaching sessions per month?
  • • Blood work and lab tests included?
  • • Access to registered dietitians or nutritionists?
  • • App, tracking tools, and resources provided?

3. Review Credentials & Results

Check program quality

  • • Are providers licensed physicians, NPs, or RDs?
  • • Do they publish patient outcomes and success rates?
  • • What certifications do they have (LegitScript, etc.)?
  • • How experienced is the care team?
  • • What do patient reviews say about support quality?

4. Understand the Commitment

Time and flexibility required

  • • Program duration (3 months, 6 months, 1 year?)
  • • Weekly time commitment for sessions and tracking
  • • Cancellation policy and flexibility
  • • Can you pause if needed?
  • • What happens after the program ends?

Red Flags to Avoid

Programs promising unrealistic weight loss (30+ lbs in 1 month)
No licensed medical providers on staff
Pressure to sign long-term contracts upfront
Unclear about medication sources or pharmacy partners
No clear refund or cancellation policy
Coaching from non-credentialed "health coaches"

Frequently Asked Questions

Common questions about GLP-1 weight loss programs

What's included in a comprehensive GLP-1 program?

Comprehensive programs typically include: prescription GLP-1 medication (semaglutide or tirzepatide), initial medical consultation, ongoing provider check-ins, personalized health coaching, nutritional guidance, lifestyle support, progress tracking tools, and access to a care team via messaging or phone.

Some programs also include blood work, body composition analysis, group support sessions, mobile apps with meal planning, and educational resources. The exact components vary by program, so check what's included in the monthly price.

Is a program worth the extra cost compared to medication-only services?

It depends on your needs. Medication-only services cost $83-$150/month and work well for self-motivated individuals who can independently manage diet, exercise, and side effects. Programs cost $149-$299/month but include coaching, accountability, and comprehensive support.

Studies show patients in structured programs with coaching have better adherence, more sustainable weight loss, and improved long-term maintenance. If you've struggled with diet and exercise before, or want guidance and accountability, programs provide better value despite higher costs.

How much time do I need to commit to a program each week?

Time commitments vary by program. Most require 30-60 minutes per week including coaching sessions (15-30 minutes), app check-ins (5-10 minutes), and tracking meals/activity (10-20 minutes).

Intensive programs like Calibrate may require 1-2 hours weekly for video sessions and activities. Lighter programs like Found or Coreage RX may only need 15-30 minutes weekly for basic check-ins. Consider your schedule when choosing a program - consistent participation matters more than choosing the most intensive option.

Can I switch programs if I'm not satisfied?

Yes, most programs operate on monthly subscriptions that you can cancel. However, some programs like Calibrate require longer commitments (6-12 months). Always read the cancellation policy before signing up.

If switching, you'll need a new consultation with the new provider, and there may be a gap in treatment. Some programs offer trial periods or money-back guarantees (like Remedy Meds' 4-month guarantee). Consider trying one month before committing to longer plans.

Do I need to meet with a coach in person or are sessions virtual?

All the programs listed here are 100% virtual/online. Coaching sessions happen via video calls (Zoom, proprietary apps), phone calls, or messaging - depending on the program. There are no in-person requirements.

This makes programs accessible nationwide and fits easily into busy schedules. Most sessions can be done from home, work, or anywhere with internet. Some programs offer flexibility between video, phone, or messaging based on your preference.

Will I gain weight back after the program ends?

Weight regain is common if you stop the medication entirely. Studies show patients regain approximately 2/3 of lost weight within a year of stopping. However, programs that emphasize habit formation and lifestyle changes can improve long-term maintenance.

Many programs transition you to a maintenance phase with continued medication at lower doses plus ongoing support. This approach helps sustain results. The advantage of comprehensive programs over medication-only is they teach sustainable habits that help even if you eventually reduce or stop medication.

Are the coaches and providers qualified healthcare professionals?

Medical oversight comes from licensed physicians, nurse practitioners, or physician assistants. Coaching may be provided by various professionals depending on the program: registered dietitians (RDs), certified health coaches, behavioral psychologists, or obesity medicine specialists.

Top programs clearly list their team credentials. Look for board-certified obesity medicine physicians, registered dietitians, and credentialed coaches. Avoid programs using only unlicensed "wellness coaches" without medical oversight. Programs like Form Health, Mochi Health, and Calibrate have strong medical and nutrition teams.

What if I don't lose weight on the program?

While GLP-1 medications are highly effective, individual results vary. Reputable programs will adjust your dosage, modify your plan, or try different medications if you're not seeing results. Some programs like Remedy Meds offer money-back guarantees if you don't lose a certain percentage.

The advantage of comprehensive programs is they can troubleshoot barriers - medication absorption issues, lifestyle factors, hormonal considerations, or other health conditions. If you're not losing weight, your care team should investigate why and adjust your treatment, not just tell you to "try harder."

Can I use my HSA or FSA to pay for a program?

Yes, most GLP-1 weight loss programs qualify for HSA/FSA payment since they're medically supervised weight loss treatments. The medication portion definitely qualifies, and many HSA/FSA administrators also cover coaching and program fees when part of a medical weight loss program.

Check with your HSA/FSA provider about specific requirements. You may need documentation from the program showing medical necessity. Most programs can provide itemized receipts showing the medical components. This can save you 20-30% on program costs depending on your tax bracket.

Do programs work with insurance for medication coverage?

Some programs help navigate insurance for brand-name medications (Wegovy, Zepbound). Sequence and Form Health specifically offer insurance navigation support. However, most insurance doesn't cover compounded GLP-1 medications from telehealth providers.

If you have insurance that covers weight loss medications, programs with insurance support can help with prior authorizations and appeals. For most people, paying cash for compounded versions through these programs ($149-$299/month total) is still more affordable than brand-name medications even with insurance copays ($500-$1000/month).

How We Ranked These Programs

Our rankings are based on comprehensive evaluation of program quality:

  • Support Quality: Coaching credentials, session frequency, and care team accessibility
  • Patient Outcomes: Published weight loss results and success rates
  • Customer Reviews: Verified patient ratings and satisfaction scores
  • Value for Money: Price relative to services and support included
  • Medical Expertise: Provider credentials and clinical approach

Note: Rankings may be influenced by affiliate relationships. We encourage you to do your own research before making a decision.

Important Notice

Compounded medications are not FDA-approved. The FDA does not evaluate compounded products for safety, effectiveness, or quality. Individual results may vary. Always consult with a qualified healthcare provider before starting any weight loss medication or program. This page contains affiliate links and rankings may be influenced by compensation.