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Comprehensive programs combining GLP-1 medications with coaching, support, and lifestyle guidance. Find the complete weight loss program that fits your needs and budget.
10
Top Programs
30K+
Reviews Analyzed
15-20%
Average Weight Loss
$99
Starting Price
A comprehensive GLP-1 weight loss program goes beyond just prescribing medication. The best programs combine prescription GLP-1 medications (semaglutide or tirzepatide) with personalized coaching, nutritional guidance, medical oversight, and ongoing support to help you achieve sustainable weight loss.
While some telehealth providers simply ship medication, complete programs offer structured support systems including behavioral coaching, dietary planning, exercise guidance, and regular check-ins with healthcare providers. This holistic approach leads to better results and helps patients maintain their weight loss long-term.
The programs ranked below offer varying levels of support and coaching. Some focus heavily on behavioral change, while others emphasize medical management. Choose based on your personal needs, budget, and the level of support you want.
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Compare top programs at a glance
| Program | Price | Rating | Coaching | Best Feature |
|---|---|---|---|---|
| Coreage RX | $99/mo | 4.4 | ✓ Personalized | Best overall value |
| Remedy Meds | $299/mo | 4.3 | ✓ Included | Money-back guarantee |
| Amble Health | $225/mo | 4.2 | ✓ Included | 34 lbs average loss |
| Calibrate | $159/mo | 4.3 | ✓ Weekly sessions | 1-year metabolic program |
| Brello Health | $133/mo | 3.7 | ✓ Dietitian calls | Best value |
Scroll down for complete rankings and detailed reviews of all programs
Best for: Those wanting affordable personalized care with exceptional value
Best for: Those wanting a comprehensive program with a results guarantee
Best for: Those prioritizing proven weight loss results with comprehensive support
Best for: Those committed to a structured year-long program with intensive coaching
Best for: Budget-conscious patients wanting coaching without premium pricing
Best for: Those wanting to address psychological aspects of eating and weight loss
Best for: Those wanting a science-driven program at an affordable price
Best for: Those wanting help navigating insurance for brand-name medications
Best for: Those wanting specialized obesity medicine expertise
Best for: Those wanting a full medical team approach
What comprehensive programs offer
How most programs work
Medication-Only Services:
Complete Programs:
Keys to maximizing your results
Patients who actively participate in coaching sessions, complete check-ins, and engage with their care team see significantly better results. Don't just take the medication - use all the resources your program provides. Attend virtual sessions, respond to messages, and track your progress consistently.
Tip: Schedule coaching sessions at consistent times to build a routine. Treat them as non-negotiable appointments.
The best programs focus on habit formation rather than restrictive diets. Work with your coach to develop sustainable eating patterns, regular movement you enjoy, and stress management techniques. The goal is lifestyle change that lasts beyond medication.
Adding healthy foods, not just restricting. Build positive habits first.
Beyond weight - energy, mood, sleep, fitness improvements matter too.
Don't hide struggles or side effects from your providers. The best outcomes happen when patients are honest about challenges, barriers, and setbacks. Your care team can adjust your plan, modify dosing, or provide additional support - but only if they know what's happening.
Most structured programs run 6-12 months for a reason. Sustainable weight loss and habit change take time. Patients who complete full programs and transition to maintenance plans have much better long-term success than those who stop after a few months.
Remember: Weight loss typically plateaus around 12-18 months. Programs help you navigate this plateau and transition to maintenance, which is where many people struggle without support.
Key factors to consider when selecting your program
How much help do you want?
What's included in the price?
Check program quality
Time and flexibility required
Common questions about GLP-1 weight loss programs
Comprehensive programs typically include: prescription GLP-1 medication (semaglutide or tirzepatide), initial medical consultation, ongoing provider check-ins, personalized health coaching, nutritional guidance, lifestyle support, progress tracking tools, and access to a care team via messaging or phone.
Some programs also include blood work, body composition analysis, group support sessions, mobile apps with meal planning, and educational resources. The exact components vary by program, so check what's included in the monthly price.
It depends on your needs. Medication-only services cost $83-$150/month and work well for self-motivated individuals who can independently manage diet, exercise, and side effects. Programs cost $149-$299/month but include coaching, accountability, and comprehensive support.
Studies show patients in structured programs with coaching have better adherence, more sustainable weight loss, and improved long-term maintenance. If you've struggled with diet and exercise before, or want guidance and accountability, programs provide better value despite higher costs.
Time commitments vary by program. Most require 30-60 minutes per week including coaching sessions (15-30 minutes), app check-ins (5-10 minutes), and tracking meals/activity (10-20 minutes).
Intensive programs like Calibrate may require 1-2 hours weekly for video sessions and activities. Lighter programs like Found or Coreage RX may only need 15-30 minutes weekly for basic check-ins. Consider your schedule when choosing a program - consistent participation matters more than choosing the most intensive option.
Yes, most programs operate on monthly subscriptions that you can cancel. However, some programs like Calibrate require longer commitments (6-12 months). Always read the cancellation policy before signing up.
If switching, you'll need a new consultation with the new provider, and there may be a gap in treatment. Some programs offer trial periods or money-back guarantees (like Remedy Meds' 4-month guarantee). Consider trying one month before committing to longer plans.
All the programs listed here are 100% virtual/online. Coaching sessions happen via video calls (Zoom, proprietary apps), phone calls, or messaging - depending on the program. There are no in-person requirements.
This makes programs accessible nationwide and fits easily into busy schedules. Most sessions can be done from home, work, or anywhere with internet. Some programs offer flexibility between video, phone, or messaging based on your preference.
Weight regain is common if you stop the medication entirely. Studies show patients regain approximately 2/3 of lost weight within a year of stopping. However, programs that emphasize habit formation and lifestyle changes can improve long-term maintenance.
Many programs transition you to a maintenance phase with continued medication at lower doses plus ongoing support. This approach helps sustain results. The advantage of comprehensive programs over medication-only is they teach sustainable habits that help even if you eventually reduce or stop medication.
Medical oversight comes from licensed physicians, nurse practitioners, or physician assistants. Coaching may be provided by various professionals depending on the program: registered dietitians (RDs), certified health coaches, behavioral psychologists, or obesity medicine specialists.
Top programs clearly list their team credentials. Look for board-certified obesity medicine physicians, registered dietitians, and credentialed coaches. Avoid programs using only unlicensed "wellness coaches" without medical oversight. Programs like Form Health, Mochi Health, and Calibrate have strong medical and nutrition teams.
While GLP-1 medications are highly effective, individual results vary. Reputable programs will adjust your dosage, modify your plan, or try different medications if you're not seeing results. Some programs like Remedy Meds offer money-back guarantees if you don't lose a certain percentage.
The advantage of comprehensive programs is they can troubleshoot barriers - medication absorption issues, lifestyle factors, hormonal considerations, or other health conditions. If you're not losing weight, your care team should investigate why and adjust your treatment, not just tell you to "try harder."
Yes, most GLP-1 weight loss programs qualify for HSA/FSA payment since they're medically supervised weight loss treatments. The medication portion definitely qualifies, and many HSA/FSA administrators also cover coaching and program fees when part of a medical weight loss program.
Check with your HSA/FSA provider about specific requirements. You may need documentation from the program showing medical necessity. Most programs can provide itemized receipts showing the medical components. This can save you 20-30% on program costs depending on your tax bracket.
Some programs help navigate insurance for brand-name medications (Wegovy, Zepbound). Sequence and Form Health specifically offer insurance navigation support. However, most insurance doesn't cover compounded GLP-1 medications from telehealth providers.
If you have insurance that covers weight loss medications, programs with insurance support can help with prior authorizations and appeals. For most people, paying cash for compounded versions through these programs ($149-$299/month total) is still more affordable than brand-name medications even with insurance copays ($500-$1000/month).
Our rankings are based on comprehensive evaluation of program quality:
Note: Rankings may be influenced by affiliate relationships. We encourage you to do your own research before making a decision.
Compounded medications are not FDA-approved. The FDA does not evaluate compounded products for safety, effectiveness, or quality. Individual results may vary. Always consult with a qualified healthcare provider before starting any weight loss medication or program. This page contains affiliate links and rankings may be influenced by compensation.
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